3-Amino-N-benzyl-6-(4-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide
نویسندگان
چکیده
In the title compound, C(21)H(16)FN(3)OS, the thieno[2,3-b]pyridine system forms dihedral angles of 10.57 (12) and 83.87 (5)° with the fluoro-phenyl ring at the 6-position and the phenyl ring of the benzyl group, respectively. In the crystal, mol-ecules are linked by weak N-H⋯N anf N-H⋯O hydrogen bonds and π-π stacking inter-actions involving fluoro-phenyl rings of adjacent mol-ecules, with a centroid-centroid distance of 3.648 (10) Å. In addition, intra-molecular N-H⋯S and N-H⋯O hydrogen bonds contribute to the stability of the mol-ecular conformation.
منابع مشابه
3-[Bis(p-tolylsulfonyl)amino]-N-(4-chlorobenzyl)-6-(3,4-dichlorophenyl)thieno[2,3-b]pyridine-2-carboxamide
In the title compound, C(35)H(26)Cl(3)N(3)O(5)S(3), the dihedral angle between the mean plane through the thieno[2,3-b]pyridine ring system and the attached benzene ring is 3.89 (6)°. The mol-ecular conformation is stabilized by an intra-molecular N-H⋯O hydrogen bond. In the crystal, mol-ecules are linked by inter-molecular C-H⋯O hydrogen bonds, forming chains parallel to [100].
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